More information
Description
Transplantation of organs, tissues or cells from a healthy donor to a patient is a complex process involving tissue typing, transplant immunology, donor availability, matching criteria, transplant coordination and skilled personnel. Oslo University Hospital requires laboratory information systems for transplant immunology integrated with decision support systems, work-up mapping and post-transplant follow-up registries.
The aim of the project is to develop a software solution completely covering the workflow of the Transplant Immunology laboratory at Oslo University Hospital, integrated with decision-making tools for combining available donors with recipients and registries to evaluate long-term patient outcome.
Our team combines excellence in IT-solutions for tissue typing and matching in Steiner LLC (Limited Liability Company), with laboratory and clinical expertise from Oslo University Hospital. In Norway, we perform all transplant immunology, organ transplantations and matching for stem cell transplantations in one center. This gives us a unique opportunity to develop and test the effect of our new Transplant Immunology decision support System (TRIMMUS), covering all steps from registering samples in the Transplant Immunology laboratory via decision support tools for combining available donors with recipients to evaluation of long-term results after transplantation. TRIMMUS will replace manual data transfer, thus reducing the risk of human errors. TRIMMUS will also present all relevant compatibility data and run algorithms to facilitate quick and appropriate counselling and decision-making, thus providing the best possible care.
Steiner LLC supplies software technology and Oslo University Hospital provides the medical expertise to develop algorithms and evaluate the performance of each algorithm, as well as the entire solution. Finally, we will use the results of the post-transplant outcome to improve pre-transplant matching algorithms.
Summary of project results
The TRIMMUS project aimed to address the challenges associated with manual data transfers between workplaces and systems in organ, tissue, or cell transplantat medicine. These manual processes are time-consuming and prone to human error, which can have significant consequences in the medical field and endangere the patient.
The project developed a software to automate routine activities in the transplantation process. This involved designing, developing, and validating a functional system linked to other medicinal programmes creating a complex and sophisticated transplant immunology decision support system that streamlines data transfer and reduces the risk of human error.
The TRIMMUS project successfully delivered functional software with a majority of the planned features. This software is expected to improve the efficiency and accuracy of transplantation processes, benefiting both medical professionals and patients.
Summary of bilateral results
The donor partner was the main initiator of the new technology and was involved in the research and joint results. Bilateral joint research and collaboration on joint results has strengthened the knowledge of all involved actors and strengthened transnational cooperation. Further collaboration is planned to develop the system further.