FBR_OC2_78 - ClockABC

Portugal (PT)

Bilateral initiative facts

Promoter:
University of Beira Interior(PT)
Bilateral initiative number:
PT-BI102
Initial cost:
€13,500
Initiative Types:
Capacity building and short-term training
Preparation of partnership project or application
Publication
Report
Study
Workshop or seminar
Partners:
Oslo University Hospital (OUS-HF)
Department of Pathology
Section of Neuropathology Research (Pahnke lab)(NO)
University of Oslo (UiO)
Translational Neurodegeneration Research and Neuropathology Lab (Pahnke lab)
Oslo
Norway (academic); www.pahnkelab.eu(NO)
Programme:
Bilateral Fund
Programme areas:
Research

More information

Description

The development of therapies for central nervous system disorders is still a major pharmacological challenge. Efflux transporters (ABC transporters) expressed at the blood brain barrier (BBB) and at the blood-cerebrospinal fluid barrier (BCSFB), are main obstacles for the delivery of therapeutic compounds into the CNS, compromising the effective treatment of brain cancer, brain metastasis from peripheral cancers and many other neurologic diseases (1). Reducing the expression and activity of these transporters while treating a brain disorder or choosing the time of the day when their activity

Information on the projects funded by the EEA and Norway Grants is provided by the Programme and Fund Operators in the Beneficiary States, who are responsible for the completeness and accuracy of this information.