Efficient Low-energy Electron Cancer Therapy with Terbium-161

Project facts

Project promoter:
Czech Technical University in Prague(CZ)
Project Number:
CZ-RESEARCH-0025
Status:
In implementation
Initial project cost:
€1,588,335
Donor Project Partners:
institute for energy Technology(NO)
Oslo University Hospital(NO)
Other Project Partners
Centrum výzkumu Řež s.r.o.(CZ)
Institute of Macromolecular Chemistry CAS(CZ)
Programme:

Description

The main aim of the project is the R&D of novel radiopharmaceuticals based on terbium-161 and novel vectors for targeted therapy of tumors. The advantage of Tb-161 is in the emission of large numbers of low energy electrons followed by gamma radiation allowing tomographic imaging and therapy follow-up. This will allow targeting of single cancer cells, micrometastases and whole tumors, particularly in early stages of diseases to increase the treatment efficiency. Project results include not only the Tb-161 production in relevant quantity, but also novel targeting molecules (see project results). Collaboration between the Czech and Norway highly experienced partners in the research, development and commercialization of the results has all prerequisites to reach the proposed results.

Information on the projects funded by the EEA and Norway Grants is provided by the Programme and Fund Operators in the Beneficiary States, who are responsible for the completeness and accuracy of this information.