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Description
1. Development of micromachined ionization interfaces allowing highly sensitive mass spectrometry analysis of pre-separated biochemical compounds.
2. Development of micromachined separation system utilizing the own patented principle of recycling chromatography in which the sample passes repeatedly though the (micro)separation column leading to a significant increase of resolution of its components.
3. Development of methodology for coupling of conventional microcolumn-based separation and on-a-chip separation techniques to mass spectrometer through the micromachined interfaces.
4. Demonstration of innovation potential of the developed technologies by showcasing two demonstrators targeting high impact applications relevant for life sciences and pharma industries.