FBR_OC2_53 - ​COVinhib - Inactivating the SARS-CoV-2 spike protein: drug discovery in the fatty acid binding pocket

Bilateral initiative facts

Promoter:
Universidade do Porto - Instituto de Ciências Biomédicas Abel Salazar (ICBAS)(PT)
Bilateral initiative number:
PT-BI080
Initial cost:
€13,500
Initiative Types:
Other
PublicationLaboratory Analysis
Partners:
Oslo University Hospital(NO)
Programme:
Programme areas:

Description

The progression of the COVID-19 pandemic to an endemic disease shows the importance of continuing to seek treatments that complement the vaccination effort. The project, aims to confirm the potential of virtual screening of selected compounds that significantly affect the binding of SARS-CoV-2 to the cellular receptor and can thus be identified as successful molecules for drug development.


This project will carry out the following steps and confirm experimentally, using inhibition assays, to test whether these selected compounds are effective in blocking the interaction between the SARS-CoV-2

Information on the projects funded by the EEA and Norway Grants is provided by the Programme and Fund Operators in the Beneficiary States, who are responsible for the completeness and accuracy of this information.